The Desert Eagle appears in the game as the "Raptor Magnum", and comes in .50 AE and .357 magnum, the latter having a two-tone pattern and fitted with a laser sight which when activated increases accuracy, but at the cost of a slightly slower rate of fire.
The Glock 17.
The Walther P99. A gold version can be unlocked.
The FN P90 appears in the PC version of the game as the "Munitions Belga PDW90". It features a green finish on the stock and frame.
The Ruger MP9.
SIG SG 551
The SIG SG 551 appears in the game as the "SG5 Commando", and comes equipped with a laser sight and either a scope or suppressor, the suppressed version being restricted to single and burst fire and has a white pistol grip, stock, and handguard. The PC version of the game adds a laser pointer to the weapon.
The Franchi SPAS-12 appears in the game as the "Frinesi Automatic 12." It can be fired pump action, or semi automatic.
Accuracy International AWM
The Accuracy International AWM appears in the game as the "Winter Tactical Sniper Rifle" and the "Winter Covert Sniper Rifle", the latter being white and fitted with a silencer while the former is green and can be loaded with armor-piercing .300 Winchester Magnum rounds. On the ground has a bolt the right way, but in your hands it has a left bolt handle.
The M202 FLASH.
The Milkor MGL appears in the game as the "Militek Mk.6" and fires grenade rounds that can be set to detonate on impact or after a timed delay. It can also be found as a fixed weapon in some multiplayer level weapon sets.
Grenades & Explosives
M67 hand grenade
The M67 hand grenade
The Walther PPK appears in the game as the "Wolfram PP7", and can be fitted with a removable silencer. A gold version can be unlocked.
A modified Glock 17 standing in for the Glock 18 appears as "Kowloon Type 40" ("Kowloon" is Chinese and part of mainland Hong Kong, indicating the weapon is supposed to be a clone manufactured in China) and is wielded infrequently by enemies. Curiously despite the burst fire function, "Glock 17" (In plain text instead of the stylized version present on an actual Glock 17) is written on the side and no selector switch is actually present (even though Bond will move his thumb to hit the non-existent switch when changing fire mode), indicating the model is based on a Glock 17.
Heckler & Koch P11
The Heckler & Koch P11 underwater pistol appears in the game as the "Korsakov K5 Dart Gun", and is used in the "Night Shift" level to subdue guards without killing them or raising an alarm. Unlike the real weapon, it only fires non-lethal tranquilizer darts instead of special-purpose underwater bullets.
The Golden Gun appears in the game as it has in all James Bond FPS games.
Heckler & Koch MP5K
The Heckler & Koch MP5K appears in the game as the "Deutsche M9K", and has a 21-round magazine (despite the real MP5K having only 15 or 30-round box magazines) and a removable silencer.
A FAMAS G1 appears highly fictionalized as an explosive laser turret in some multiplayer maps, mounted on a turret base with a gun shield in front of the receiver.
Objective Individual Combat Weapon
The Objective Individual Combat Weapon appears in the game as the "Advanced Individual Munitions System-20" ("AIMS-20" for short) and can fire 5.56mm rifle rounds or 20mm HE-Frag grenade rounds, both of which are targeted via a built-in Infra-Red scope. It is similar to the "tank buster" used by Colonel Moon in Die Another Day.
Browning M2HB Heavy Machine Gun
The Browning M2HB heavy machine gun appears in multiplayer mode only and is available only with certain weapon sets.
AT-420 Sentinel / AT-600 Scorpion
The Sentinel and the Scorpion are fictional shoulder fired, reloadable, multi-launch rocket systems. The Sentinel can be fired in either unguided or TV-guided modes, while the Scorpion replaces the TV-guided mode with heat-seeking. The Scorpion is also available as a fixed weapon on some multiplayer weapon sets. Both weapons use the same model. Drake uses one of those models in the last level.
Grenades and Explosives
Mk 2 Hand Grenade
The Mk 2 hand grenade appears in console versions the game as the "Fragmentation Grenade".
Radio Controlled Helicopter
If this option is turned on during multiplayer, the players can operate a small radio controlled helicopter with AT-600 rocket launchers mounted on the aircraft. (Also equipped with a chain-gun)
Radio-Controlled Miniature M1 Abrams Main Battle Tank
With the "vehicles" option enabled, the player can operate a miniature Abrams battle tank with a mounted grenade launcher and M2 .50 caliber machine gun.
Briefcase Sentry Gun
Appears as the "Ronin". A briefcase with a surprise, it hides a minigun and camera to shoot anyone that crosses its path that isn't the one that originally set it up. It is available to the player during multiplayer, and is sometimes used by the enemy in the missions to guard hallways or rooms. Can be controlled remotely by the player that set it up in multiplayer (isn't mobile).
Phoenix Samurai Laser Rifle
A fictitious laser gun visually based off of the M16, appears to be chrome-plated and has a semi-auto and over-charge setting. With the gun-emplacements option on sometimes a turret with this technology appears in a beam or over-charge setting. These weapons use laser energy and never runs out of ammo, although it does overheat.
GE M134 Minigun
The GE M134 Minigun appears in multiplayer mode only as a fixed weapon and is available only with certain weapon sets. Care must be taken when using the weapon, as prolonged bursts can cause it to overheat and stop working until it cools back down.