Agents of the Department of Extra-Normal Operations (DEO) are seen carrying Glock 17s.
Glock 17 3rd Generation - 9x19mm
Hank Henshaw (David Harewood) has the pistol holstered in Season 2's premiere "The Adventures of Supergirl" (S2E01).
Glock 19
Alex Danvers (Chyler Leigh) is seen carrying a Glock 19 as her standard carry weapon.
Glock 19 (3rd Generation) - 9x19mm
Alex Danvers (Chyler Leigh) has the pistol holstered in Season 2's premiere "The Adventures of Supergirl" (S2E01).
Beretta Px4 Storm
A Beretta Px4 Storm pistol is used in Season 2's premiere "The Adventures of Supergirl" (S2E01).
Beretta Px4 Storm 9mm
A Beretta Px4 Storm pistol is used in Season 2's premiere "The Adventures of Supergirl" (S2E01).
Other
Drone Miniguns
In Season 2's premiere "The Adventures of Supergirl" (S2E01), drones are seen armed with miniaturized rotary machine guns that appear to be on the M134 minigun.
General Electric M134 - 7.62x51mm NATO
Drones armed with Minigun-style weapons are seen in Season 2's premiere "The Adventures of Supergirl" (S2E01).