The following weapons were used in the film Horrible Bosses:
Smith & Wesson Model 66
Dave Harken (Kevin Spacey) pulls a Smith & Wesson Model 66 with Hogue grips when confronting Bobby Pellitt (Colin Farrell). Near the end of the film, he holds it on Nick Hendricks (Jason Bateman), Dale Arbus (Charlie Day), and Kurt Buckman (Jason Sudeikis) after he rams their car.
All of the officers and detectives carry full-sized Glock 18C's. The ports featured on Glock 18Cs are very different from Glock 17C ports. The Glock 17C has two cutouts on the slide directly over the front part of the barrel. The Glock 18C has one large cutout over a sliced/ported barrel as well as one thinned out, machined section on the slide behind the breech to help keep it cool.